Benzocaine 4% wipes were evaluated in an independent, double-blind, placebo controlled clinical trial to test the effect, safety and tolerability of benzocaine 4% wipes in men who had PE. Preliminary results were presented at the annual American Urological Association’s annual meeting in 2017.
Who was tested?
The study enrolled 26 men (18 years and older) with PE in monogamous, heterosexual relationships. The average Intravaginal Ejaculatory Latency Time (IELT) of the men was less than two minutes as measured with a stopwatch. IELT measures how long it takes a man to reach orgasm after entering the vagina.
How were they studied?
About two-thirds of the men were randomly selected to use benzocaine 4% wipes for two months while one-third used a placebo wipe. After a month, the men on the placebo were allowed to use the real benzocaine 4% wipes. The study measured how long it took to orgasm by looking at the IELT over the course of two months with a questionnaire to assess how they felt emotionally.
The men treated with benzocaine 4% wipes showed a statistically significant improvement in IELT after the first month of treatment. Where they lasted just 75 seconds at the start of the study, the men lasted, on average, 2.75 minutes after the first month of treatment. They experienced even greater improvement after the second month with an average of 5.5 minutes. The men averaged about 10 sexual episodes over that two months
The treated men also reported greater improvement in control of their ejaculation, more satisfaction with sexual intercourse and less distress and frustration related to sex. After two months of treatment, 82 percent of men in the study were no longer considered to have PE.
Men in the study reported no transfer of benzocaine to their partner during sex and only two of the men experienced side effects (mild headache, back pain and a mild irritation on the penis) that resolved on its own.
Practice makes perfect
It takes practice for anyone to learn which areas are the most sensitive. Exploring when to apply the benzocaine and discovering your most sensitive areas is a process. We recommend including some behavioral modification techniques as an added way to gain control and learn about your sexual responses. Together, the topical anesthetics and exercises can help control your reactions to sexual sensations.
The medical profession is recognizing how vital your role is in discovering the best treatment for you. A recent article in the International Journal of Urology concluded that “moving forward, urologists, psychiatrists and primary care doctors alike have to tailor their treatment of PE to the patient as an individual to improve outcomes. Each presentation of PE is unique in and of itself.”