Allergy relief


Generic Astelin

Azelastine hydrochloride 0.1% solution

A fast-acting nasal antihistamine spray.

Works in as little as 15 minutes.

FDA-approved to relieve symptoms of allergic rhinitis.

Safe for use every day.

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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a healthcare provider.

How to Use

Spray the medication in each nostril as prescribed.

Common Side Effects

Bitter taste, nosebleeds, and sleepiness.

Transparent Manufacturing

Azelastine is manufactured in Canada.

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Allergy medication works best when taken every day.

Be sure to continue using your medication as directed, even after your symptoms have improved.

If you have any questions about your treatment, message your doctor at any time at

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What is azelastine?

Azelastine is a type of medication known as a second-generation antihistamine. Antihistamine medications block the action of histamine, an inflammatory chemical the body releases during an allergic reaction. The release of histamine leads to a number of symptoms including watery eyes, runny nose, sneezing, and itchy skin. Azelastine helps stop these symptoms from happening.

How does azelastine differ from Astelin?

Azelastine is the generic form of the brand name medication, Astelin. The two medications are considered equivalent. The U.S. Food and Drug Administration requires that generic drugs demonstrate bioequivalence to the brand name drug, which means they act the same way in the body and are expected to produce the same effects as the original brand name drug.

How does azelastine work?

Azelastine works by blocking the H1 receptors on cells, which are receptors that are normally activated by the chemical histamine. When the body is exposed to an allergen, immune cells (called mast cells and basophils) release histamine. Since azelastine blocks histamine from activating the H1 receptors, the symptoms that are typically caused by histamine are lessened. Azelastine also has anti-inflammatory effects and reduces congestion.

How should azelastine be taken?

Azelastine comes as a nasal spray that delivers the medication directly to the inside of the nose. It is used two times per day, once in the morning and once in the evening. If possible, try to take the medication at the same time each day. To properly use the nasal spray, follow the directions for use that accompany the medication. You may also find these steps helpful:

  1. Before first use, pump the bottle about 5 times until a mist appears. Also do this if the product hasn’t been used in 3+ days.
  2. Shake the bottle gently.
  3. Blow your nose to clear it before each use.
  4. Slightly tilt your head forward and insert the applicator tip into your nostril.
  5. Hold the applicator tip inside your nose and point the tip towards the outer corner of your eye. It’s helpful to use the opposite hand with each nostril to ensure that the tip is facing the outer corner of your eye. The goal is NOT to spray the medication straight back. You also do not want to point the tip towards the midline of the nose (where the septum is) because that can cause nosebleeds.
  6. Close off the other nostril with a finger. Breathe in, and press the pump to release the spray while inhaling.
  7. Hold your breath for a few seconds, and breathe out slowly through your mouth after each spray.
  8. Alternate nostrils after each pump (e.g. right-left-right-left)
  9. After using the spray, gently sniff.
  10. Wipe the tip of the applicator with a clean tissue after each use.

What if you miss a dose?

If you accidentally miss a dose, take it when you remember. However, if your next dose is supposed to be within a couple of hours, skip the missed dose and resume your normal schedule. Do not take a double dose.

What if you take more than you are prescribed?

Using too much azelastine is generally not considered dangerous. However, it may cause drowsiness and frequent spraying of the medication into your nose could cause trauma to the lining inside of your nose, which could lead to nosebleeds. If you have sprayed too much azelastine and are experiencing symptoms, contact a healthcare provider immediately.

Is buying azelastine online safe?

With Roman, you can always be sure you are getting genuine medication. Roman dispenses drugs that are FDA approved and manufactured by pharmaceutical companies that adhere to the FDA’s manufacturing standards for finished drug products. In fact, you will likely find many of the same manufacturers we use in your local pharmacy.

Side effects

Azelastine commonly causes a bitter taste in the mouth which can be unpleasant for some users. Azelastine may also be mildly sedating. Users should exercise caution when taking azelastine and should be aware that mental alertness may be decreased. This can impact the ability to drive or operate machinery. Azelastine may cause nosebleeds. If this occurs, please stop using the medication and see your in-person healthcare provider.

Additional possible side effects include bronchospasm, atrial fibrillation, anaphylactoid reactions, dyspnea, blurred vision, conjunctivitis, depression, sinus tachycardia, hypertension, furunculosis, stomatitis, elevated hepatic enzymes, constipation, glossitis, hematuria, contact dermatitis, confusion, tolerance, chest pain, palpitations, urinary retention, ocular irritation, rhinitis, headache, drowsiness, pharyngitis, fatigue, ocular pain, pruritus, dysesthesia, nasal irritation, xerostomia, nausea, laryngitis, nasal dryness, nasal congestion, throat irritation, hyperkinesis, vertigo, dizziness, anxiety, hypoesthesia, flushing, diarrhea, weight gain, appetite stimulation, abdominal pain, increased urinary frequency, amenorrhea, malaise, back pain, myalgia, sneezing, rhinalgia, epistaxis, sinusitis, cough, vomiting, dysgeusia, fever, infection, paresthesias, insomnia, xerophthalmia, and rash.

Important safety information

The information here is taken from the Prescriber’s Digital Reference (PDR), which can be found here.

Contraindications & precautions

  • Azelastine should not be used by anybody who has an allergy or sensitivity to azelastine.
  • Azelastine should not be used by anybody who is pregnant or nursing.

Drug interactions

  • Azelastine should not be used with alcohol or with other medications that depress the central nervous system.
  • The full list of medication interactions is listed in the PDR.

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