The individual ingredients in Roman’s Testosterone Support supplement are generally well tolerated. However, there are certain people who should refrain from use or should use caution due to possible interactions with medical conditions or medications. People with Wilson disease should not take supplements that contain copper. Pregnant women and men with hormone-sensitive prostate cancer should not take this supplement. Additionally, individuals with autoimmune diseases (e.g. systemic lupus erythematosus, multiple sclerosis, rheumatoid arthritis), kidney disease, or low blood pressure should talk to their healthcare provider first and should use caution when taking this product. Roman’s Testosterone Support supplement may also interact with certain medications and should be used with caution by anybody taking antibiotics, anticonvulsants, barbiturates, benzodiazepines, bisphosphonates, cholestyramine, corticosteroids, diuretics, immunosuppressive medications, orlistat, penicillamine, proton pump inhibitors, or thyroid medications. If you have a health condition or are taking medication and have questions about whether Roman’s Testosterone Support supplement is safe for you, talk with your healthcare provider before taking the supplement.